Differential methylation at MHC in CD4(+) T cells is associated with multiple sclerosis independently of HLA-DRB1

BACKGROUND: Although many genetic variants have been associated with multiple sclerosis (MS) risk, they do not explain all the disease risk and there remains uncertainty as to how these variants contribute to disease. DNA methylation is an epigenetic mechanism that can influence gene expression and...

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Detalles Bibliográficos
Autores principales: Maltby, Vicki E., Lea, Rodney A., Sanders, Katherine A., White, Nicole, Benton, Miles C., Scott, Rodney J., Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516341/
https://www.ncbi.nlm.nih.gov/pubmed/28729889
http://dx.doi.org/10.1186/s13148-017-0371-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516341/
https://www.ncbi.nlm.nih.gov/pubmed/28729889
http://dx.doi.org/10.1186/s13148-017-0371-1

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