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Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats

BACKGROUND: Heparanase, a mammalian endo-β-D-glucoronidase that specifically degrades heparan sulfate, has been implicated in inflammation and ischemic stroke. However, the role of heparanase in neuroinflammatory response in subarachnoid hemorrhage (SAH) has not yet been investigated. This study was...

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Detalles Bibliográficos
Autores principales: Changyaleket, Benjarat, Chong, Zhao Zhong, Dull, Randal O., Nanegrungsunk, Danop, Xu, Haoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516362/
https://www.ncbi.nlm.nih.gov/pubmed/28720149
http://dx.doi.org/10.1186/s12974-017-0912-8