A versatile papaya mosaic virus (PapMV) vaccine platform based on sortase-mediated antigen coupling

BACKGROUND: Flexuous rod-shaped nanoparticles made of the coat protein (CP) of papaya mosaic virus (PapMV) have been shown to trigger innate immunity through engagement of toll-like receptor 7 (TLR7). PapMV nanoparticles can also serve as a vaccine platform as they can increase the immune response t...

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Detalles Bibliográficos
Autores principales: Thérien, Ariane, Bédard, Mikaël, Carignan, Damien, Rioux, Gervais, Gauthier-Landry, Louis, Laliberté-Gagné, Marie-Ève, Bolduc, Marilène, Savard, Pierre, Leclerc, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516373/
https://www.ncbi.nlm.nih.gov/pubmed/28720097
http://dx.doi.org/10.1186/s12951-017-0289-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516373/
https://www.ncbi.nlm.nih.gov/pubmed/28720097
http://dx.doi.org/10.1186/s12951-017-0289-y

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