Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathways

High-frequency stimulation of the medial perforant path triggers robust phosphorylation of ribosomal protein S6 (rpS6) in activated dendritic domains and granule cell bodies. Here we dissect the signaling pathways responsible for synaptically driven rpS6 phosphorylation in the dentate gyrus using ph...

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Detalles Bibliográficos
Autores principales: Pirbhoy, Patricia Salgado, Farris, Shannon, Steward, Oswald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516686/
https://www.ncbi.nlm.nih.gov/pubmed/28716954
http://dx.doi.org/10.1101/lm.044974.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516686/
https://www.ncbi.nlm.nih.gov/pubmed/28716954
http://dx.doi.org/10.1101/lm.044974.117

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