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Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity

OBJECTIVE: Insulin resistance (IR) is one of the earliest predictors of type 2 diabetes. However, diagnosis of IR is limited. High fat fed mouse models provide key insights into IR. We hypothesized that early features of IR are associated with persistent changes in gene expression (GE) and endeavore...

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Detalles Bibliográficos
Autores principales: Chaudhuri, Rima, Khoo, Poh Sim, Tonks, Katherine, Junutula, Jagath R, Kolumam, Ganesh, Modrusan, Zora, Samocha-Bonet, Dorit, Meoli, Christopher C, Hocking, Samantha, Fazakerley, Daniel J, Stöckli, Jacqueline, Hoehn, Kyle L, Greenfield, Jerry R, Yang, Jean Yee Hwa, James, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516867/
https://www.ncbi.nlm.nih.gov/pubmed/28725461
http://dx.doi.org/10.1038/npjsba.2015.10