Evidence for prehistoric origins of the G2019S mutation in the North African Berber population

The most common cause of the monogenic form of Parkinson’s disease known so far is the G2019S mutation of the leucine-rich repeat kinase 2 (LRRK2) gene. Its frequency varies greatly among ethnic groups and geographic regions ranging from less than 0.1% in Asia to 40% in North Africa. This mutation h...

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Detalles Bibliográficos
Autores principales: Ben El Haj, Rafiqua, Salmi, Ayyoub, Regragui, Wafa, Moussa, Ahmed, Bouslam, Naima, Tibar, Houyam, Benomar, Ali, Yahyaoui, Mohamed, Bouhouche, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517005/
https://www.ncbi.nlm.nih.gov/pubmed/28723952
http://dx.doi.org/10.1371/journal.pone.0181335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517005/
https://www.ncbi.nlm.nih.gov/pubmed/28723952
http://dx.doi.org/10.1371/journal.pone.0181335

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