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FISH-ing for captured contacts: towards reconciling FISH and 3C

Chromosome conformation capture (3C) and fluorescence in-situ hybridization (FISH) are two widely-used technologies that provide distinct readouts of 3D chromosome organization. While both technologies can assay locus-specific organization, how to integrate views from 3C, or genome-wide Hi-C, and FI...

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Detalles Bibliográficos
Autores principales: Fudenberg, Geoff, Imakaev, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517086/
https://www.ncbi.nlm.nih.gov/pubmed/28604723
http://dx.doi.org/10.1038/nmeth.4329