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An Integrative Analysis Reveals a Central Role of P53 Activation via MDM2 in Zika Virus Infection Induced Cell Death

Zika virus (ZIKV) infection is an emerging global threat that is suspected to be associated with fetal microcephaly. However, the molecular mechanisms underlying ZIKV disease pathogenesis in humans remain elusive. Here, we investigated the human protein interaction network associated with ZIKV infec...

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Detalles Bibliográficos
Autores principales: Teng, Yue, Liu, Shufeng, Guo, Xiaocan, Liu, Shuxia, Jin, Yuan, He, Tongtong, Bi, Dehua, Zhang, Pei, Lin, Baihan, An, Xiaoping, Feng, Dan, Mi, Zhiqiang, Tong, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517408/
https://www.ncbi.nlm.nih.gov/pubmed/28775961
http://dx.doi.org/10.3389/fcimb.2017.00327