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Baseline value of intrahepatic HBV DNA over cccDNA predicts patient’s response to interferon therapy

Methodology for accurate quantification of intra-hepatic cccDNA has long been a technical challenge, yet it is highly desired in the clinic. Here, we developed a sensitive method for quantification of intrahepatic cccDNA in liver biopsies from patients, which allowed to predict patient’s response to...

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Detalles Bibliográficos
Autores principales: Mu, Di, Yuan, Fang-Chao, Chen, Yu, Jiang, Xiao-Yan, Yan, Liang, Jiang, Ling-Yu, Gong, Jian-Ping, Zhang, Da-Zhi, Ren, Hong, Liao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517439/
https://www.ncbi.nlm.nih.gov/pubmed/28725013
http://dx.doi.org/10.1038/s41598-017-05242-y