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Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2(A) Receptor to Promote the Establishment of Infection
Adenosine is an endogenously released purine nucleoside that signals through four widely expressed G protein-coupled receptors: A1, A2(A), A2(B), and A3. Of these, A(2A)R is recognized as mediating major adenosine anti-inflammatory activity. During cutaneous leishmaniasis, adenosine induces immunosu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517451/ https://www.ncbi.nlm.nih.gov/pubmed/28775724 http://dx.doi.org/10.3389/fimmu.2017.00815 |