Leishmania infantum Parasites Subvert the Host Inflammatory Response through the Adenosine A2(A) Receptor to Promote the Establishment of Infection

Adenosine is an endogenously released purine nucleoside that signals through four widely expressed G protein-coupled receptors: A1, A2(A), A2(B), and A3. Of these, A(2A)R is recognized as mediating major adenosine anti-inflammatory activity. During cutaneous leishmaniasis, adenosine induces immunosu...

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Detalles Bibliográficos
Autores principales: Lima, Mikhael H. F., Sacramento, Lais A., Quirino, Gustavo F. S., Ferreira, Marcela D., Benevides, Luciana, Santana, Alynne K. M., Cunha, Fernando Q., Almeida, Roque P., Silva, João S., Carregaro, Vanessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517451/
https://www.ncbi.nlm.nih.gov/pubmed/28775724
http://dx.doi.org/10.3389/fimmu.2017.00815

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