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Cyclic di-GMP regulates Mycobacterium tuberculosis resistance to ethionamide

Tuberculosis is still on the top of infectious diseases list on both mobility and mortality, especially due to drug-resistance of Mycobacterium tuberculosis (M.tb). Ethionamide (ETH) is one of effective second line anti-TB drugs, a synthetic compound similar to isoniazid (INH) structurally, with exi...

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Detalles Bibliográficos
Autores principales: Zhang, Hai-Nan, Xu, Zhao-Wei, Jiang, He-Wei, Wu, Fan-Lin, He, Xiang, Liu, Yin, Guo, Shu-Juan, Li, Yang, Bi, Li-Jun, Deng, Jiao-Yu, Zhang, Xian-En, Tao, Sheng-Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517500/
https://www.ncbi.nlm.nih.gov/pubmed/28725053
http://dx.doi.org/10.1038/s41598-017-06289-7