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X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid

Polysialic acid (polySia) is a homopolymeric saccharide that is associated with some neuroinvasive pathogens and is found on selective cell types in their eukaryotic host. The presence of a polySia capsule on these bacterial pathogens helps with resistance to phagocytosis, cationic microbial peptide...

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Detalles Bibliográficos
Autores principales: Lizak, Christian, Worrall, Liam J., Baumann, Lars, Pfleiderer, Moritz M., Volkers, Gesa, Sun, Tianjun, Sim, Lyann, Wakarchuk, Warren, Withers, Stephen G., Strynadka, Natalie C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517516/
https://www.ncbi.nlm.nih.gov/pubmed/28724897
http://dx.doi.org/10.1038/s41598-017-05627-z