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X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid
Polysialic acid (polySia) is a homopolymeric saccharide that is associated with some neuroinvasive pathogens and is found on selective cell types in their eukaryotic host. The presence of a polySia capsule on these bacterial pathogens helps with resistance to phagocytosis, cationic microbial peptide...
Autores principales: | Lizak, Christian, Worrall, Liam J., Baumann, Lars, Pfleiderer, Moritz M., Volkers, Gesa, Sun, Tianjun, Sim, Lyann, Wakarchuk, Warren, Withers, Stephen G., Strynadka, Natalie C. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517516/ https://www.ncbi.nlm.nih.gov/pubmed/28724897 http://dx.doi.org/10.1038/s41598-017-05627-z |
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