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Opposite, bidirectional shifts in excitation and inhibition in specific types of dorsal horn interneurons are associated with spasticity and pain post-SCI

Spasticity, a common complication after spinal cord injury (SCI), is frequently accompanied by chronic pain. The physiological origin of this pain (critical to its treatment) remains unknown, although spastic motor dysfunction has been related to the hyperexcitability of motoneurons and to changes i...

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Detalles Bibliográficos
Autores principales: Kopach, Olga, Medvediev, Volodymyr, Krotov, Volodymyr, Borisyuk, Anya, Tsymbaliuk, Vitaliy, Voitenko, Nana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517549/
https://www.ncbi.nlm.nih.gov/pubmed/28724992
http://dx.doi.org/10.1038/s41598-017-06049-7