Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase

A novel series of hybrid analogues of monastrol-1,3,5-triazine were designed and developed via one-pot synthesis using Bi(NO(3))(3) as a catalyst. Entire compounds were evaluated for their anticancer activity against HeLa (cervical cancer), MCF-7 (breast cancer), HL-60 (Human promyelocytic leukemia)...

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Detalles Bibliográficos
Autores principales: Srivastava, Jitendra Kumar, Pillai, Girinath G., Bhat, Hans Raj, Verma, Amita, Singh, Udaya Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517562/
https://www.ncbi.nlm.nih.gov/pubmed/28724908
http://dx.doi.org/10.1038/s41598-017-05934-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517562/
https://www.ncbi.nlm.nih.gov/pubmed/28724908
http://dx.doi.org/10.1038/s41598-017-05934-5

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