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Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase
A novel series of hybrid analogues of monastrol-1,3,5-triazine were designed and developed via one-pot synthesis using Bi(NO(3))(3) as a catalyst. Entire compounds were evaluated for their anticancer activity against HeLa (cervical cancer), MCF-7 (breast cancer), HL-60 (Human promyelocytic leukemia)...
Autores principales: | Srivastava, Jitendra Kumar, Pillai, Girinath G., Bhat, Hans Raj, Verma, Amita, Singh, Udaya Pratap |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517562/ https://www.ncbi.nlm.nih.gov/pubmed/28724908 http://dx.doi.org/10.1038/s41598-017-05934-5 |
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