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Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease

Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods for clearing, labeling, and imaging whole organs such as th...

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Detalles Bibliográficos
Autores principales: Hsueh, Brian, Burns, Vanessa M., Pauerstein, Philip, Holzem, Katherine, Ye, Li, Engberg, Kristin, Wang, Ai-Chi, Gu, Xueying, Chakravarthy, Harini, Arda, H. Efsun, Charville, Gregory, Vogel, Hannes, Efimov, Igor R., Kim, Seung, Deisseroth, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517617/
https://www.ncbi.nlm.nih.gov/pubmed/28724969
http://dx.doi.org/10.1038/s41598-017-05614-4