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Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease
Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods for clearing, labeling, and imaging whole organs such as th...
Autores principales: | Hsueh, Brian, Burns, Vanessa M., Pauerstein, Philip, Holzem, Katherine, Ye, Li, Engberg, Kristin, Wang, Ai-Chi, Gu, Xueying, Chakravarthy, Harini, Arda, H. Efsun, Charville, Gregory, Vogel, Hannes, Efimov, Igor R., Kim, Seung, Deisseroth, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517617/ https://www.ncbi.nlm.nih.gov/pubmed/28724969 http://dx.doi.org/10.1038/s41598-017-05614-4 |
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