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Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children

Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We therefore sought to identify transcriptional signatures in whole blood of Indian...

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Detalles Bibliográficos
Autores principales: Gjøen, John Espen, Jenum, Synne, Sivakumaran, Dhanasekaran, Mukherjee, Aparna, Macaden, Ragini, Kabra, Sushil K., Lodha, Rakesh, Ottenhoff, Tom H. M., Haks, Marielle C., Doherty, Timothy Mark, Ritz, Christian, Grewal, Harleen M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517635/
https://www.ncbi.nlm.nih.gov/pubmed/28724962
http://dx.doi.org/10.1038/s41598-017-05057-x