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Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for future effective management of cancer. In this report, we show t...

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Detalles Bibliográficos
Autores principales: AlShamaileh, Hadi, Wang, Tao, Xiang, Dongxi, Yin, Wang, Tran, Phuong Ha-Lien, Barrero, Roberto A., Zhang, Pei-Zhuo, Li, Yong, Kong, Lingxue, Liu, Ke, Zhou, Shu-Feng, Hou, Yingchun, Shigdar, Sarah, Duan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517644/
https://www.ncbi.nlm.nih.gov/pubmed/28724889
http://dx.doi.org/10.1038/s41598-017-05859-z