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Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells
The development of chemoresistance and inability in elimination of cancer stem cells are among the key limitations of cancer chemotherapy. Novel molecular therapeutic strategies able to overcome such limitations are urgently needed for future effective management of cancer. In this report, we show t...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517644/ https://www.ncbi.nlm.nih.gov/pubmed/28724889 http://dx.doi.org/10.1038/s41598-017-05859-z |