Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice

Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders remains elusive. Here, we report the effects of Pc...

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Detalles Bibliográficos
Autores principales: Hayashi, Shuichi, Inoue, Yoko, Hattori, Satoko, Kaneko, Mari, Shioi, Go, Miyakawa, Tsuyoshi, Takeichi, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517645/
https://www.ncbi.nlm.nih.gov/pubmed/28724954
http://dx.doi.org/10.1038/s41598-017-06374-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517645/
https://www.ncbi.nlm.nih.gov/pubmed/28724954
http://dx.doi.org/10.1038/s41598-017-06374-x

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