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Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice
Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders remains elusive. Here, we report the effects of Pc...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517645/ https://www.ncbi.nlm.nih.gov/pubmed/28724954 http://dx.doi.org/10.1038/s41598-017-06374-x |