Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with the intenti...

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Detalles Bibliográficos
Autores principales: Terada, Daiki, Voet, Arnout R. D., Noguchi, Hiroki, Kamata, Kenichi, Ohki, Mio, Addy, Christine, Fujii, Yuki, Yamamoto, Daiki, Ozeki, Yasuhiro, Tame, Jeremy R. H., Zhang, Kam Y. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517649/
https://www.ncbi.nlm.nih.gov/pubmed/28724971
http://dx.doi.org/10.1038/s41598-017-06332-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517649/
https://www.ncbi.nlm.nih.gov/pubmed/28724971
http://dx.doi.org/10.1038/s41598-017-06332-7

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