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Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with the intenti...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517649/ https://www.ncbi.nlm.nih.gov/pubmed/28724971 http://dx.doi.org/10.1038/s41598-017-06332-7 |