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Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes()

The discovery and development of novel anthelmintic classes is essential to sustain the control of socioeconomically important parasitic worms of humans and animals. With the aim of offering novel, lead-like scaffolds for drug discovery, Compounds Australia released the ‘Open Scaffolds’ collection c...

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Detalles Bibliográficos
Autores principales: Preston, Sarah, Jiao, Yaqing, Baell, Jonathan B., Keiser, Jennifer, Crawford, Simon, Koehler, Anson V., Wang, Tao, Simpson, Moana M., Kaplan, Ray M., Cowley, Karla J., Simpson, Kaylene J., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517787/
https://www.ncbi.nlm.nih.gov/pubmed/28732272
http://dx.doi.org/10.1016/j.ijpddr.2017.05.004