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Examining the role of unmeasured confounding in mediation analysis with genetic and genomic applications

BACKGROUND: In mediation analysis if unmeasured confounding is present, the estimates for the direct and mediated effects may be over or under estimated. Most methods for the sensitivity analysis of unmeasured confounding in mediation have focused on the mediator-outcome relationship. RESULTS: The U...

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Detalles Bibliográficos
Autores principales: Lutz, Sharon M., Thwing, Annie, Schmiege, Sarah, Kroehl, Miranda, Baker, Christopher D., Starling, Anne P., Hokanson, John E., Ghosh, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517807/
https://www.ncbi.nlm.nih.gov/pubmed/28724417
http://dx.doi.org/10.1186/s12859-017-1749-y