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Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity

BACKGROUND: Neuroinflammation plays a major role in postoperative cognitive dysfunction (POCD). Accumulated evidence indicates that cannabinoid receptor type 2 (CB2R) can mediate anti-inflammatory and immunomodulatory effects in part by controlling microglial activity. However, the impact of CB2R on...

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Detalles Bibliográficos
Autores principales: Sun, Lingling, Dong, Rui, Xu, Xin, Yang, Xi, Peng, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518095/
https://www.ncbi.nlm.nih.gov/pubmed/28724382
http://dx.doi.org/10.1186/s12974-017-0913-7