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EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

BACKGROUND: Epidermal growth factor receptor (EGFR), a well-known oncogenic driver, contributes to the initiation and progression of a wide range of cancer types. Aberrant lipid metabolism including highly produced monounsaturated fatty acids (MUFA) is recognized as a hallmark of cancer. However, ho...

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Detalles Bibliográficos
Autores principales: Zhang, Jiqin, Song, Fei, Zhao, Xiaojing, Jiang, Hua, Wu, Xiuqi, Wang, Biao, Zhou, Min, Tian, Mi, Shi, Bizhi, Wang, Huamao, Jia, Yuanhui, Wang, Hai, Pan, Xiaorong, Li, Zonghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518108/
https://www.ncbi.nlm.nih.gov/pubmed/28724430
http://dx.doi.org/10.1186/s12943-017-0704-x