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EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer
BACKGROUND: Epidermal growth factor receptor (EGFR), a well-known oncogenic driver, contributes to the initiation and progression of a wide range of cancer types. Aberrant lipid metabolism including highly produced monounsaturated fatty acids (MUFA) is recognized as a hallmark of cancer. However, ho...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518108/ https://www.ncbi.nlm.nih.gov/pubmed/28724430 http://dx.doi.org/10.1186/s12943-017-0704-x |