Cargando…

Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance

BACKGROUND: Malaria remains a major public health burden and resistance has emerged to every antimalarial on the market, including the frontline drug, artemisinin. Our limited understanding of Plasmodium biology hinders the elucidation of resistance mechanisms. In this regard, systems biology approa...

Descripción completa

Detalles Bibliográficos
Autores principales: Carey, Maureen A., Papin, Jason A., Guler, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518114/
https://www.ncbi.nlm.nih.gov/pubmed/28724354
http://dx.doi.org/10.1186/s12864-017-3905-1