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Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance
BACKGROUND: Malaria remains a major public health burden and resistance has emerged to every antimalarial on the market, including the frontline drug, artemisinin. Our limited understanding of Plasmodium biology hinders the elucidation of resistance mechanisms. In this regard, systems biology approa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518114/ https://www.ncbi.nlm.nih.gov/pubmed/28724354 http://dx.doi.org/10.1186/s12864-017-3905-1 |