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Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic inflammation of the joints, leading to bone erosion and joint dysfunction. Despite the recent successes of disease-modifying anti-rheumatic drugs (DMARDs), there is still clinical need for understanding the...

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Detalles Bibliográficos
Autores principales: MacLauchlan, Susan, Zuriaga, Maria A., Fuster, José J., Cuda, Carla M., Jonason, Jennifer, Behzadi, Fernanda, Duffen, Jennifer Parker, Haines, G. Kenneth, Aprahamian, Tamar, Perlman, Harris, Walsh, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518154/
https://www.ncbi.nlm.nih.gov/pubmed/28724439
http://dx.doi.org/10.1186/s13075-017-1375-0