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High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

BACKGROUND: ETS2 is a downstream effector of the RAS/RAF/ERK pathway, which plays a critical role in the development of malignant tumor. However, the clinical impact of ETS2 expression in AML remains unknown. METHODS: In this study, we evaluated the prognostic significance of ETS2 expression using t...

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Detalles Bibliográficos
Autores principales: Fu, Lin, Fu, Huaping, Wu, Qingyun, Pang, Yifan, Xu, Keman, Zhou, Lei, Qiao, Jianlin, Ke, Xiaoyan, Xu, Kailin, Shi, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518161/
https://www.ncbi.nlm.nih.gov/pubmed/28724426
http://dx.doi.org/10.1186/s12967-017-1260-2