Postzygotic single‐nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations

The roles and characteristics of postzygotic single‐nucleotide mosaicisms (pSNMs) in autism spectrum disorders (ASDs) remain unclear. In this study of the whole exomes of 2,361 families in the Simons Simplex Collection, we identified 1,248 putative pSNMs in children and 285 de novo SNPs in children...

Descripción completa

Detalles Bibliográficos
Autores principales: Dou, Yanmei, Yang, Xiaoxu, Li, Ziyi, Wang, Sheng, Zhang, Zheng, Ye, Adam Yongxin, Yan, Linlin, Yang, Changhong, Wu, Qixi, Li, Jiarui, Zhao, Boxun, Huang, August Yue, Wei, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518181/
https://www.ncbi.nlm.nih.gov/pubmed/28503910
http://dx.doi.org/10.1002/humu.23255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518181/
https://www.ncbi.nlm.nih.gov/pubmed/28503910
http://dx.doi.org/10.1002/humu.23255

Ejemplares similares