Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression

Polydatin (PD), a resveratrol glycoside, has been shown to protect renal function in diabetic nephropathy (DN), but the underlying molecular mechanism remains unclear. This study demonstrates that PD stabilize the mitochondrial morphology and attenuate mitochondrial malfunction in both KKAy mice and...

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Detalles Bibliográficos
Autores principales: Ni, Zheng, Tao, Liang, Xiaohui, Xu, Zelin, Zhao, Jiangang, Liu, Zhao, Song, Weikang, Huo, Hongchao, Xu, Qiujing, Wang, Xin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518182/
https://www.ncbi.nlm.nih.gov/pubmed/28383775
http://dx.doi.org/10.1002/jcp.25943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518182/
https://www.ncbi.nlm.nih.gov/pubmed/28383775
http://dx.doi.org/10.1002/jcp.25943

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