Cargando…

Leucine elicits myotube hypertrophy and enhances maximal contractile force in tissue engineered skeletal muscle in vitro

The amino acid leucine is thought to be important for skeletal muscle growth by virtue of its ability to acutely activate mTORC1 and enhance muscle protein synthesis, yet little data exist regarding its impact on skeletal muscle size and its ability to produce force. We utilized a tissue engineering...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Neil R.W., Turner, Mark C., Farrington, Robert, Player, Darren J., Lewis, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518187/
https://www.ncbi.nlm.nih.gov/pubmed/28409828
http://dx.doi.org/10.1002/jcp.25960