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Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission‐VDAC1‐HK2‐mPTP‐mitophagy axis

The cardiac microvascular system, which is primarily composed of monolayer endothelial cells, is the site of blood supply and nutrient exchange to cardiomyocytes. However, microvascular ischemia/reperfusion injury (IRI) following percutaneous coronary intervention is a woefully neglected topic, and...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Zhang, Ying, Hu, Shunying, Shi, Chen, Zhu, Pingjun, Ma, Qiang, Jin, Qinhua, Cao, Feng, Tian, Feng, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518188/
https://www.ncbi.nlm.nih.gov/pubmed/28398674
http://dx.doi.org/10.1111/jpi.12413