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Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission‐VDAC1‐HK2‐mPTP‐mitophagy axis
The cardiac microvascular system, which is primarily composed of monolayer endothelial cells, is the site of blood supply and nutrient exchange to cardiomyocytes. However, microvascular ischemia/reperfusion injury (IRI) following percutaneous coronary intervention is a woefully neglected topic, and...
Autores principales: | Zhou, Hao, Zhang, Ying, Hu, Shunying, Shi, Chen, Zhu, Pingjun, Ma, Qiang, Jin, Qinhua, Cao, Feng, Tian, Feng, Chen, Yundai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518188/ https://www.ncbi.nlm.nih.gov/pubmed/28398674 http://dx.doi.org/10.1111/jpi.12413 |
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