TGF‐β signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes

The electrogenic sodium bicarbonate cotransporter NBCe1 (SLC4A4) expressed in astrocytes regulates intracellular and extracellular pH. Here, we introduce transforming growth factor beta (TGF‐β) as a novel regulator of NBCe1 transcription and functional expression. Using hippocampal slices and primar...

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Detalles Bibliográficos
Autores principales: Khakipoor, Shokoufeh, Ophoven, Christian, Schrödl‐Häußel, Magdalena, Feuerstein, Melanie, Heimrich, Bernd, Deitmer, Joachim W., Roussa, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518200/
https://www.ncbi.nlm.nih.gov/pubmed/28568893
http://dx.doi.org/10.1002/glia.23168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518200/
https://www.ncbi.nlm.nih.gov/pubmed/28568893
http://dx.doi.org/10.1002/glia.23168

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