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TGF‐β signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes
The electrogenic sodium bicarbonate cotransporter NBCe1 (SLC4A4) expressed in astrocytes regulates intracellular and extracellular pH. Here, we introduce transforming growth factor beta (TGF‐β) as a novel regulator of NBCe1 transcription and functional expression. Using hippocampal slices and primar...
Autores principales: | Khakipoor, Shokoufeh, Ophoven, Christian, Schrödl‐Häußel, Magdalena, Feuerstein, Melanie, Heimrich, Bernd, Deitmer, Joachim W., Roussa, Eleni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518200/ https://www.ncbi.nlm.nih.gov/pubmed/28568893 http://dx.doi.org/10.1002/glia.23168 |
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