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Influence of Meals and Glycemic Changes on QT Interval Dynamics

Thorough QT/QTc studies have become an integral part of early drug development programs, with major clinical and regulatory implications. This analysis expands on existing pharmacodynamic models of QT interval analysis by incorporating the influence of glycemic changes on the QT interval in a semime...

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Detalles Bibliográficos
Autores principales: Cirincione, Brenda, Sager, Philip T., Mager, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518218/
https://www.ncbi.nlm.nih.gov/pubmed/28543601
http://dx.doi.org/10.1002/jcph.933