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Influence of Meals and Glycemic Changes on QT Interval Dynamics
Thorough QT/QTc studies have become an integral part of early drug development programs, with major clinical and regulatory implications. This analysis expands on existing pharmacodynamic models of QT interval analysis by incorporating the influence of glycemic changes on the QT interval in a semime...
Autores principales: | Cirincione, Brenda, Sager, Philip T., Mager, Donald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518218/ https://www.ncbi.nlm.nih.gov/pubmed/28543601 http://dx.doi.org/10.1002/jcph.933 |
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