Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels

Although neuroglobin confers neuroprotection against Alzheimer's disease (AD) pathology, its expression becomes downregulated in late‐stage AD. Here, we provide evidence that indicates that this decrease is associated with the AD‐linked angiopathy. While wild‐type mice of different ages show up...

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Detalles Bibliográficos
Autores principales: Van Acker, Zoë P., Luyckx, Evi, Van Leuven, Wendy, Geuens, Eva, De Deyn, Peter P., Van Dam, Debby, Dewilde, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518225/
https://www.ncbi.nlm.nih.gov/pubmed/28391636
http://dx.doi.org/10.1002/1873-3468.12651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518225/
https://www.ncbi.nlm.nih.gov/pubmed/28391636
http://dx.doi.org/10.1002/1873-3468.12651

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