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Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels
Although neuroglobin confers neuroprotection against Alzheimer's disease (AD) pathology, its expression becomes downregulated in late‐stage AD. Here, we provide evidence that indicates that this decrease is associated with the AD‐linked angiopathy. While wild‐type mice of different ages show up...
Autores principales: | Van Acker, Zoë P., Luyckx, Evi, Van Leuven, Wendy, Geuens, Eva, De Deyn, Peter P., Van Dam, Debby, Dewilde, Sylvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518225/ https://www.ncbi.nlm.nih.gov/pubmed/28391636 http://dx.doi.org/10.1002/1873-3468.12651 |
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