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Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase

The protein methylome in mammalian mitochondria has been little studied until recently. Here, we describe that lysine‐368 of human citrate synthase is methylated and that the modifying enzyme, localized in the mitochondrial matrix, is methyltransferase‐like protein 12 (METTL12), a member of the fami...

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Detalles Bibliográficos
Autores principales: Rhein, Virginie F., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518231/
https://www.ncbi.nlm.nih.gov/pubmed/28391595
http://dx.doi.org/10.1002/1873-3468.12649