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Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase
The protein methylome in mammalian mitochondria has been little studied until recently. Here, we describe that lysine‐368 of human citrate synthase is methylated and that the modifying enzyme, localized in the mitochondrial matrix, is methyltransferase‐like protein 12 (METTL12), a member of the fami...
Autores principales: | Rhein, Virginie F., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518231/ https://www.ncbi.nlm.nih.gov/pubmed/28391595 http://dx.doi.org/10.1002/1873-3468.12649 |
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