Evolution of Cost-Free Resistance under Fluctuating Drug Selection in Pseudomonas aeruginosa

Antibiotic resistance evolves rapidly in response to drug selection, but it can also persist at appreciable levels even after the removal of the antibiotic. This suggests that many resistant strains can both be resistant and have high fitness in the absence of antibiotics. To explore the conditions...

Descripción completa

Detalles Bibliográficos
Autores principales: Melnyk, Anita H., McCloskey, Nicholas, Hinz, Aaron J., Dettman, Jeremy, Kassen, Rees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518267/
https://www.ncbi.nlm.nih.gov/pubmed/28744479
http://dx.doi.org/10.1128/mSphere.00158-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518267/
https://www.ncbi.nlm.nih.gov/pubmed/28744479
http://dx.doi.org/10.1128/mSphere.00158-17

Ejemplares similares