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Evolution of Cost-Free Resistance under Fluctuating Drug Selection in Pseudomonas aeruginosa
Antibiotic resistance evolves rapidly in response to drug selection, but it can also persist at appreciable levels even after the removal of the antibiotic. This suggests that many resistant strains can both be resistant and have high fitness in the absence of antibiotics. To explore the conditions...
Autores principales: | Melnyk, Anita H., McCloskey, Nicholas, Hinz, Aaron J., Dettman, Jeremy, Kassen, Rees |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518267/ https://www.ncbi.nlm.nih.gov/pubmed/28744479 http://dx.doi.org/10.1128/mSphere.00158-17 |
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