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The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles

Chlamydia trachomatis delivers multiple type 3 secreted effector proteins to host epithelial cells to manipulate cytoskeletal functions, membrane dynamics, and signaling pathways. TepP is the most abundant effector protein secreted early in infection, but its molecular function is poorly understood....

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Detalles Bibliográficos
Autores principales: Carpenter, Victoria, Chen, Yi-Shan, Dolat, Lee, Valdivia, Raphael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518268/
https://www.ncbi.nlm.nih.gov/pubmed/28744480
http://dx.doi.org/10.1128/mSphere.00207-17