A mouse model of systemic lupus erythematosus responds better to soluble TACI than to soluble BAFFR, correlating with depletion of plasma cells

The TNF family cytokines B‐cell activating factor (BAFF) and a proliferation‐inducing ligand (APRIL) support plasma cell survival. It is known that inhibitors of BAFF only (BAFFR‐Fc) or BAFF and APRIL (TACI‐Fc) administered early enough in an NZB/NZW F1 mouse model of systemic lupus erythematosus (S...

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Detalles Bibliográficos
Autores principales: Haselmayer, Philipp, Vigolo, Michele, Nys, Josquin, Schneider, Pascal, Hess, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518279/
https://www.ncbi.nlm.nih.gov/pubmed/28383107
http://dx.doi.org/10.1002/eji.201746934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518279/
https://www.ncbi.nlm.nih.gov/pubmed/28383107
http://dx.doi.org/10.1002/eji.201746934

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